Antibody Screening of Healthy Blood Donors: It’s Time to Make it Mandatory

Red cell unexpected alloantibodies can be present in healthy donors who were either transfused previously or pregnant previously. Presence of irregular erythrocyte alloantibodies can occasionally cause severe transfusion reaction if a large amount of plasma or whole blood is transfused as in massive transfusions and in pediatric patients. Here we are presenting a case report of a donor who had red cell alloantibody. The purpose of highlighting this case report is to know the significance of detecting irregular erythrocyte antibodies in healthy donors.